Synthesis of 4,5-decamethyleneimidazole, 4,5-decamethyleneoxazole, 4,5-decamethyleneisoxazole, 4,5-decamethyleneimidazolone-2, and 4,5-decamethylenepyrazole from cyclododecanone derivatives

4,5-Decamethyleneimidazole, 4,5-decamethyleneoxazole, and 4,5-decamethyleneimidazolone-2 were synthesized by reactions of 2-bromocyclododecanone and 2-hydroxycyclododecanone with formamide, ammonium formate, and urea, respectively. Condensation of 2-formylcyclododecanone with hydroxylamine and hydrazine hydrate resulted in 4,5-decamethyleneisoxazole, and 4,5-decamethylenepyrazole, respectively.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 891–893, May, 1994.