Two new xanthones isolated from the stem bark of Garcinia lancilimba |
| |
| Authors: | Yang Nian-Yun Han Quan-Bin Cao Xin-Wei Qiao Chun-Feng Song Jing-Zheng Chen Shi-Lin Yang Da-Jian Yiu Hillary Xu Hong-Xi |
| |
| Institution: | Chinese Medicine Laboratory, Hong Kong Jockey Club Institute of Chinese Medicine, Hong-Kong, PR China. |
| |
| Abstract: | Two new xanthones, 1,5,6-trihydroxy-6',6'-dimethyl-2H-pyrano(2',3':3,4)-2-(3-methylbut-2-enyl)xanthone (1) and 1,6,7-trihydroxy-6',6'-dimethyl-2H-pyrano(2',3':3,2)-4-(3-methylbut-2-enyl)xanthone (2), have been isolated from the stem bark of Garcinia lancilimba (Guttiferae), together with six known xanthones. Their structures were identified on the basis of extensive spectral evidence including detailed 2D NMR and HR-MS data. Two new compounds showed moderate inhibitory effect on human breast cancer MDA-MB-435S cell line. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
