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Osteomyelitis: Sensitivity of 0.064 T MRI, three-phase bone scanning and indium scanning with biopsy proof
Authors:Michael R. Williamson    Ronald W. Quenzer    Robert D. Rosenberg    Andrew J. Meholic    Brian Eisenberg    Mary C. Espinosa  Michael F. Hartshorne
Affiliation:

a University of New Mexico School of Medicine, Department of Radiology, Albuquerque, NM 87131-5336, USA

b University of New Mexico School of Medicine, Department of Infectious Diseases, Albuquerque, NM 87131-5336, USA

c Veteran Affairs Medical Center, Department of Radiology, 2100 Ridgecrest Drive SE, Albuquerque, NM 87108, USA

d Virginia Mason Clinic, 1100 9th Avenue, P.O. Box 900 C-5S, Seattle, WA 98111, USA

Abstract:
We compared the ability of magnetic resonance imaging (MRI) using a 0.064 T permanent magnet, three-phase bone scanning, and indium-labeled white blood cell (111In-WBC) scanning, to diagnose osteomyelitis. Twenty-three patients underwent biopsy. All patients were examined at presentation with all three modalities. Sensitivities for each modality were calculated using biopsy as a gold standard. The results were 72% for MRI, 68% for bone scan, and 45% for 111In-WBC. Specificities were not calculated because of lack of negative biopsies. MRI was as sensitive as bone scanning in the diagnosis of osteomyelitis. All modalities had lower than previously reported sensitivities for imaging osteomyelitis.
Keywords:Author Keywords: Magnetic resonance imaging   Radionuclide imaging   Comparative studies   Osteomyelitis   Bone infection   Indium radioisotopes   Technetium radioisotopes   Indium-111   Technetium-99m
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