From allene to allene: a palladium-catalyzed approach to beta-allenyl butenolides and their application to the synthesis of polysubstituted benzene derivatives |
| |
| Authors: | Ma Shengming Gu Zhenhua Deng Youqian |
| |
| Affiliation: | State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, PR China. masm@mail.sioc.ac.cn |
| |
| Abstract: | ![]()
An allene to allene protocol for the synthesis of beta-allenyl butenolides in moderate to high yields from 2,3-allenoic acids and propargylic carbonates catalyzed by Pd(OAc)2-TFP has been developed; the products were applied successfully to the Diels-Alder reaction with electron-deficient alkynes to afford polysubstituted benzene derivatives with an excellent regioselectivity. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
