An aquatic host-guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin |
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| Authors: | José M Rivera Mariana Martín-Hidalgo Jean C Rivera-Ríos |
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| Affiliation: | Department of Chemistry, University of Puerto Rico Río Piedras Campus, San Juan, PR 00931, USA. jmrivortz@mac.com. |
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| Abstract: | ![]()
We describe the synthesis of a fluorescent deoxyguanosine derivative that co-assembles (in water) with an unlabeled analogue into a heteromeric supramolecular G-quadruplex, which forms a host-guest complex with doxorubicin as evidenced by FRET experiments. |
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