Gemini surfactants from natural amino acids |
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Authors: | Lourdes Pérez Aurora PinazoRamon Pons MRosa Infante |
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Institution: | Instituto de Química Avanzada de Cataluña, CSIC, Jordi Girona 18-26, 08008 Barcelona, Spain |
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Abstract: | In this review, we report the most important contributions in the structure, synthesis, physicochemical (surface adsorption, aggregation and phase behaviour) and biological properties (toxicity, antimicrobial activity and biodegradation) of Gemini natural amino acid-based surfactants, and some potential applications, with an emphasis on the use of these surfactants as non-viral delivery system agents. Gemini surfactants derived from basic (Arg, Lys), neutral (Ser, Ala, Sar), acid (Asp) and sulphur containing amino acids (Cys) as polar head groups, and Geminis with amino acids/peptides in the spacer chain are reviewed. |
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Keywords: | Gemini surfactants Natural amino acid-based surfactants Toxicity Aggregation Delivery systems |
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