Synthesis,characterization and antibacterial activity of some new pyrazole based Schiff bases |
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| Authors: | Shridhar Malladi Arun M Isloor Shrikrishna Isloor DS Akhila Hoong-Kun Fun |
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| Institution: | 1. Medicinal Chemistry Division, Department of Chemistry, National Institute of Technology-Karnataka, Surathkal, Mangalore 575 025, India;2. Department of Microbiology, Veterinary College, Hebbal, KVAFSU, Bangalore, India;3. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Kingdom of Saudi Arabia |
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| Abstract: | In the present study a series of new Schiff bases were synthesized. All the synthesized compounds were characterized by IR, 1H NMR, mass spectral and elemental analyses. Newly synthesized compounds were screened for their antibacterial (Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa) activity. The results revealed that, compounds 3f and 3c have exhibited significant biological activity against the tested microorganisms. |
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| Keywords: | Schiff bases Triazoles Pyrazoles Antimicrobial activity |
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