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3-Alkylpyridines III. Total synthesis of both enantiomers of the antineoplastic marine alkaloid niphatesine D
Authors:F. Bracher  T. Papke
Affiliation:(1) Institut für Pharmazeutische Chemie der Technischen Universität Braunschweig, D-38106 Braunschweig, Germany
Abstract:
Summary A five-step synthesis of both enantiomers of the marine alkaloid niphatesine D (3), starting from the readily available enantiomeric hydroxyalkylthiophenes5 andent-5, is described.Dedicated to Prof. Dr.E. Reimann on the occasion of his 60th birthday
Keywords:Alkaloid  Niphatesine D  3-Alkylpyridines  Reductive desulfurization
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