Immunosuppressive terpenoids from Tripterygium wilfordii |
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| Authors: | Qian Shen Zhi Yao Yoshihisa Takaishi Yan Wen Zhang Hong Quan Duan |
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| Affiliation: | a School of Pharmaceutical Sciences, Basic Medical Research Center of Tianjin, Tianjin Medical University, Tianjin 300070, China;b Department of Immunology, Tianjin Medical University, Tianjin 300070, China;c Faculty of Pharmaceutical Sciences, University of Tokushima, Tokushima 770-8505, Japan |
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| Abstract: | Two new terpenes,triptobenzene P (1) and wilforone (2) were isolated from Tripterygium wilfordii,as well as 10 known terpenes.Their structures were elucidated by spectroscopic methods.Compounds 2-4,8,10,and 11 showed significantimmunosuppressive activities. |
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| Keywords: | Tripterygium wilfordii Diterpone Triterpone Immunosuppressive activity |
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