首页 | 本学科首页   官方微博 | 高级检索  
     


Novel thermoresponsive and pH-responsive aggregates from self-assembly of triblock copolymer PSMA-b-PNIPAAm-b-PSMA
Authors:Zhou Junfeng  Wang Li  Yang Qiang  Liu Qingquan  Yu Haojie  Zhao Zhenrong
Affiliation:State Key Laboratory of Chemical Engineering, Zhejiang University, Hangzhou 310027, People's Republic of China.
Abstract:A series of novel triblock copolymers of poly(stearyl methacrylate)-b-poly(N-isopropylacrylamide)-b-poly(stearyl methacrylate) (PSMA-b-PNIPAAm-b-PSMA) with different molecular weights was synthesized through carboxyl-terminated trithiocarbonates as a highly efficient RAFT agent via reversible addition-fragmentation chain transfer (RAFT) polymerization. The resultant polymers were characterized by 1H NMR, FT-IR spectroscopy, and GPC. By varying the organic solvent used in the self-assembly procedure and adjusting the copolymer composition, multiple morphologies ranging from vesicles and core-shell spherical aggregates with different dimensions to pearl-necklace-like aggregates were obtained. The aggregates showed thermoresponsive and pH-responsive properties through the lower critical solution temperature (LCST) of PNIPAAm and the two carboxyl end groups of the copolymer.
Keywords:
本文献已被 PubMed 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号