Multicomponent Transformation of Isoindoline‐1,3‐diimine (=1H‐Isoindole‐1,3(2H)‐diimine), Acetylenic Esters,and Triphenylphosphine to Novel Dihydropyrimido[2,1‐a]isoindole Derivatives |
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| Authors: | Robabeh Baharfar Saadieh Mohajer |
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| Institution: | 1. Department of Chemistry, University of Mazandaran, Babolsar, Iran (phone: +98‐1125342350;2. fax: +98‐1125342350) |
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| Abstract: | The three‐component reaction of the zwitterions generated from dialkyl acetylenedicarboxylates (=dialkyl but‐2‐ynedioates and triphenylphosphine (Ph3P) with isoindoline‐1,3‐diimine (=1H‐isoindole‐1,3(2H)‐diimine) is described (Scheme 1). This reaction affords the corresponding special type of substituted dihydropyrimido2,1‐a]isoindole derivatives in good yields without using any catalyst and activation (Table). |
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| Keywords: | Pyrimido[2 1‐a]isoindoles dihydro‐ Acetylenedicarboxylates dialkyl Isoindoline‐1 3‐diimine Multicomponent reactions |
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