Evaluation of the biosafety of cyanoacrylate adhesive in vitro |
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| Authors: | M. S. Belova D. G. Korovina V. N. Tsygankov A. B. Varava I. P. Savchenkova O. A. Legon’kova |
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| Affiliation: | 1.Vishnevskii Institute of Surgery, Ministry of Health of Russia,Moscow,Russia;2.Kovalenko All-Russian Scientific Research Institute of Experimental Veterinary Sciences,Moscow,Russia |
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| Abstract: | This paper considers the evaluation of the biosafety of cyanoacrylate adhesive in vitro on human multipotent mesenchymal stem cells. This adhesive is intended for medical use, in particular, for X-ray and endovascular interventions. A toxicity study was carried out in a culture of multipotent mesenchymal stem cells isolated from human subcutaneous fat. As a result of the work, the concentration of cyanoacrylate adhesive in lipiodol was chosen, which has the lowest toxicity. |
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