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Comparative study on the antioxidant activities of extracts of Coreopsis tinctoria flowering tops from Kunlun Mountains,Xinjiang, north-western China
Authors:Xincheng Yao  Chengzhi Gu  Liping Tian  Xinbing Wang
Institution:1. College of Pharmacy, Shihezi University, Shihezi, 832000Xinjiang, P.R. China;2. Ministry of Education Key Laboratory of Xinjiang Endemic Phytomedicine Resources, Shihezi University, Shihezi, 832000Xinjiang, P.R. China;3. School of Chemistry and Chemical Engineering, Shihezi University, Shihezi, 832002Xinjiang, P.R. China
Abstract:Coreopsis tinctoria flowering tops (CTFs) from the Kunlun Mountains in Xinjing (north-western China) have been used for tea production for about a century. This study aims to assess the antioxidant activities and total phenolic, flavonoid and proanthocyanidin contents of various solvent extracts of CTF. CTF was extracted using n-hexane, chloroform, ethyl acetate, n-butanol, 75% aqueous ethanol (AEE) and water. The antioxidant activities of the CTF extracts were investigated through DPPH, ABTS, *OH, *O2, total antioxidant capacity and reducing power assays. The results showed that n-butanol extract showed the highest contents of total phenols and flavonoids, with DPPH, ABTS and *OH radical-scavenging activities with IC50 values of 134, 90.72 and 13.8 μg mL? 1, respectively. The AEE demonstrated the strongest DPPH and ABTS radical-scavenging activities, with IC50 values of 103 and 75.16 μg mL? 1, respectively. Given its high antioxidant effect, CTF is a good source of natural antioxidants or functional food materials.
Keywords:antioxidant activity  Coreopsis tinctoria Nutt  radical scavenging activity
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