New cyclic tetrapeptide from the coral-derived endophytic bacteria Brevibacterium sp. L-4 collected from the South China Sea |
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| Authors: | Bing-Xin Liu Qiong Guo Guang-Tian Peng Xi-Xin He Xiao-Jie Chen Ling-Fang Lei |
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| Institution: | School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou 510006, P.R. China |
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| Abstract: | One new cyclic tetrapeptide cyclic-(Tyr-Ala-Leu-Ser) (1) along with four natural compounds firstly obtained 3H-imidazole-4-carboxylic acid (2), 2-methyl-3H-imidazole-4-carboxylic acid (3), 3-ethylidene-6-isopropyl-piperazine-2,5-dione (4), and 3-isobutylidene-6-methyl piperazine-2,5-dione (5) have been isolated from the coral derived endophytic bacteria Brevibacterium sp. L-4 collected from the South China Sea. Their structures were elucidated through spectroscopic techniques including NMR (1D and 2D), MS, and EA, and their relative configurations were also assigned by NMR analysis. |
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| Keywords: | Brevibacterium sp L-4 coral derived endophytic bacteria tetrapeptide 3-ylidene-2 5-piperazinediones |
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