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A new triterpenoid glycoside from the leaves and stems of Duranta repens
Authors:Chisato Furusawa  Shin Yasuda  Hiroshi Tsuji  Show Ito  Hiroyuki Miyashita  Hitoshi Yoshimitsu
Institution:1. School of Agriculture, Tokai University, Minamiaso 5435, Aso, Kumamoto 869-1404, Japan;2. Faculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Nishi-ku, Kumamoto 860-0082, Japan
Abstract:A new triterpenoid glycoside (1) was isolated from the methanol extract of the leaves and stems of Duranta repens L. (Verbenaceae) along with 14 known compounds consisting of eight triterpenoids, four iridoids, one phenylethanoid glycoside and one flavonoid. The chemical structure of 1 was determined to be bayogenin 3-O-β-D-glucopyranoside]-28-O-α-L-rhamnopyranosyl-(1→5)-O-β-D-apiofuranosyl-(1→4)-O-α-L-rhamnopyranosyl-(1→2)-O-α-L-arabinopyranosyl] ester, based on spectroscopic data. In addition, the inhibitory effects of the isolates on lipoxygenase activity were examined. Among them, acteoside and apigenin resulted in 94 ± 3.6% and 82 ± 4.7% inhibition, respectively, at 0.5 mM.
Keywords:Duranta repens  Vabenaceae  triterpenoid glycoside  lipoxygenase inhibitory effect
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