Icosandrin,a novel peltogynoid from the fruits of Phytolacca icosandra (Phytolaccaceae) |
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| Authors: | Elier Galarraga Montes Juan Manuel Amaro-Luis |
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| Institution: | 1. Departamento de Química, Edificio de Química y Procesos, Universidad Simón Bolívar (USB), Apartado 89000, Caracas 1080A, Venezuelaeliergalarraga@usb.ve;3. Laboratorio de Productos Naturales, Departamento de Química, Facultad de Ciencias, Universidad de Los Andes (ULA), Mérida 5101, Venezuela |
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| Abstract: | Besides the known compounds ( ± ) 3,3-bis-demethylpinoresinol (2), americanol A (3), spergulagenic acid (4), epi-acetylaleuritolic acid (5), 6′-palmityl-α-spinateryl-d-glucoside (6a) and 6′-palmityl-δ7-stigmastenyl-d-glucoside (6b), a novel peltogynoid (1) named icosandrin was obtained from the dried fruits of Phytolacca icosandra. This new compound was characterised by 1D-/2D-NMR, UV, IR and HR-MS techniques as 11ξ-methoxy-6,7-methylenedioxy-2]benzopyrano-4,3-b]1]-benzopyran-4-one. Toxicity of 1 was assessed through the Brine Shrimp Lethality Assay. Lignan 2 is reported for the first time in Phytolaccaceae family. |
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| Keywords: | Phytolaccaceae Phytolacca icosandra peltogynoids lignans BSLA |
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