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A Conductive polylactic acid/polyaniline porous scaffold via freeze extraction for potential biomedical applications |
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| Authors: | Saiful Izwan Abd Razak Farah Nuruljannah Dahli Izzati Fatimah Wahab Mohammed Rafiq Abdul Kadir Ida Idayu Muhamad Abdul Halim Mohd Yusof |
| Institution: | 1. IJN-UTM Cardiovascular Engineering Centre, Universiti Teknologi Malaysia, Skudai, Johor, Malaysia;2. Medical Devices and Technology Group, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Skudai, Johor, Malaysiasaifulizwan@utm.my;4. Medical Devices and Technology Group, Faculty of Biosciences and Medical Engineering, Universiti Teknologi Malaysia, Skudai, Johor, Malaysia;5. Faculty of Chemical and Energy Engineering, Universiti Teknologi Malaysia, Skudai, Johor, Malaysia;6. Faculty of Chemical and Energy Engineering, Universiti Teknologi Malaysia, Skudai, Johor, Malaysia |
| Abstract: | This paper reports for the first time a simple yet effective method for fabricating a conductive and highly porous scaffold material made up of polylactic acid (PLA) and conducting polyaniline (PANI). The electrical percolation state was successfully obtained at 3 wt% of PANI inclusions and reached a conductivity level of useable tissue engineering applications at 4 wt%. In addition, preliminary bioactivity test results indicated that the protonating agent could form a chelate at the scaffold surface leading to good in-vitro apatite forming ability during biomimetic immersion. This new conductive scaffold has potential as a suitable biomedical material that requires electrical conductivity. |
| Keywords: | Conductive scaffold electrical conductivity freeze extraction polylactic acid polyaniline scaffold tissue engineering |