Environmentally benign and highly regioselective ring opening of epoxides accelerated by ultrasound irradiation |
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| Authors: | Mohamed Mahmoud Nasef Jahanbakhsh Asadi Ebrahim Abouzari-Lotf Arshad Ahmad Reihaneh Malakooti |
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| Affiliation: | 1. Institute of Hydrogen Energy, Universiti Teknologi Malaysia, 54100, Kuala Lumpur, Malaysia;2. Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, 54100 Kuala Lumpur, Malaysiamahmoudeithar@cheme.utm.my;4. Metabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran;5. Malaysia-Japan International Institute of Technology, Universiti Teknologi Malaysia, 54100 Kuala Lumpur, Malaysia;6. Nanochemistry Research Laboratory, Department of Chemistry, University of Birjand, Birjand, Iran |
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| Abstract: | Regioselective ring opening of aliphatic and aromatic epoxides with nitrogen heterocycles such as indoles and imidazoles was accelerated using an ultrasonic technique as a green approach. An optimized procedure with the catalyst of choice, MCM-41, represents a real alternative to the conventional reaction protocols owing to the catalyst recyclability, simplicity, green conditions and time-saving aspects. |
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| Keywords: | Ultrasound irradiation regioselective ring opening MCM-41 solvent-free |
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