Chemical composition,N-nitrosamine inhibition and antioxidant and antimicrobial properties of essential oil from Coreopsis tinctoria flowering tops |
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| Authors: | Xincheng Yao Xinbing Wang Chengzhi Gu Hong Zeng Wen Chen |
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| Affiliation: | 1. College of Pharmacy, Shihezi University, Shihezi 832000, Xinjiang, P.R. China;2. Ministry of Education Key Laboratory of Xinjiang Endemic Phytomedicine Resources, Shihezi University, Shihezi 832000, Xinjiang, P.R. China;3. School of Chemistry and Chemical Engineering, Shihezi University, Shihezi 832002, Xinjiang, P.R. China;4. Key Laboratory of Protection and Utilization of Biological Resources, College of Life Science, Tarim University, Alar 843300, Xinjiang, P.R. China |
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| Abstract: | Coreopsis tinctoria flowering (CTF) tops from the Kunlun Mountains in Xinjing (north-western China) have been used for tea production for about a century. This study was to assess antioxidant, nitrite-scavenging and N-nitrosamine inhibitory and antimicrobial activities of the essential oil extracted from CTF tops. The essential oil was extracted through hydrodistillation and its chemical compositions were analysed by GC–MS. Seventy compounds of the oil were identified, representing 81.87% of total oil. The antioxidant capacities of the oil with IC50 values for scavenging DPPH and ABTS were 287.66 ± 12.60 and 1.251 ± 0.127 μg mL? 1, respectively. The nitrite-scavenging and N-nitrosamine inhibitory activities (IC50) were 0.3912 ± 0.0127 and 0.6564 ± 0.036 μg mL? 1, respectively. The oil has a certain antimicrobial capacity, but its capacity was weaker than that of penicillinG (24 μg mL? 1). The oil showed antioxidant and antimicrobial capacities and had a stronger nitrite-scavenging and N-nitrosamine inhibitory properties. |
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| Keywords: | antimicrobial activity antioxidant activity chemical compositions Coreopsis tinctoria Nutt essential oil N-nitrosamine inhibition |
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