A new flavonol glycoside from the florets of Carthamus tinctorius L. |
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| Authors: | Xue Xie Jianming Zhou Lin Sun Hongda Zhang Yiwu Zhao Yaling Song |
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| Affiliation: | 1. Jiangsu Kanion Pharmaceutical Co., Ltd, Jiangsu, Lianyungang 222001, P.R. China;2. State Key Laboratory of New-Tech for Chinese Medicine Pharmaceutical Process, Jiangsu, Lianyungang 222001, P.R. China |
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| Abstract: | One new flavonol glycoside, 6-hydroxykaempferol-3-O-β-D-glucoside-7-O-β-D-glucuronide (1), together with eight known flavonoids and three known quinochalcones, was isolated from the florets of Carthamus tinctorius L. Their structures were determined by extensive spectroscopic analyses. Their cardioprotective effects against H2O2-induced apoptosis in H9c2 cells were also evaluated; compounds 1, 2, 4–5, 7–10 and 12 provided significant protective effects on H2O2-induced H9c2 cells at the concentration of 25 μg/mL. |
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| Keywords: | Carthamus tinctorius L cardioprotective activitiy 6-hydroxykaempferol-3-O-β- smallcaps smallerCapital" >D-glucoside-7-O-β- smallcaps smallerCapital" >D-glucuronide |
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