Ruthenium‐Catalyzed Transfer‐Hydrogenative Cyclization of 1,6‐Diynes with Hantzsch 1,4‐Dihydropyridine as a H2 Surrogate |
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| Authors: | Prof?Dr Yoshihiko Yamamoto Shota Mori Dr Masatoshi Shibuya |
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| Institution: | Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Chikusa, Nagoya 464‐8601 (Japan), Fax: (+81)?52 747 6800 |
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| Abstract: | The transfer‐hydrogenative cyclization of 1,6‐diynes with Hantzsch 1,4‐dihydropyridine as a H2 surrogate was performed in the presence of a cationic ruthenium catalyst of the type Cp′Ru(MeCN)3PF6]. Exocyclic 1,3‐dienes or their 1,4‐hydrogenation products, cycloalkenes, were selectively obtained, depending on the substrate structure and the reaction conditions. |
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| Keywords: | alkenes alkynes cyclization ruthenium transfer hydrogenation |
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