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Synthesis of Difluorocatharanthine and Investigation of its Biomimetic Coupling with Vindoline |
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| Authors: | Dr. Emerson Giovanelli Dr. Lionel Moisan Dr. Sébastien Leroux Dr. Sébastien Comesse Dr. Bernard Rousseau Dr. Paul Hellier Dr. Marc Nicolas Dr. Eric Doris |
| Affiliation: | 1. CEA, iBiTecS, Service de Chimie Bioorganique et de Marquage, 91191 Gif‐sur‐Yvette (France), Fax: (+33)?169‐08‐79‐91;2. Les Laboratoires Pierre Fabre, Centre de Développement de Chimie Industrielle, 16 rue Jean Rostand, 81600 Gaillac (France) |
| Abstract: | |
| Keywords: | anticancer drugs biomimetic synthesis fluorination alkaloids |