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2-Quinazolylguanidines in Heterocyclization Reactions. 2. Condensation with α,β-Unsaturated Carbonyl Compounds
Authors:Kh S Shikhaliev  A V Falaleev  G I Ermolova  A S Solov'ev
Institution:(1) Voronezh State University, Voronezh, 394693, Russia
Abstract:4,6,6-Trimethyl-1,4-dihydropyrimidines have been synthesized by condensation of 2-quinazolylguanidines with mesityl oxide. The analogous reaction with benzalacetone leads to unstable 4-methyl-6-phenyl-1,4-dihydropyrimidines, which are oxidized to the corresponding 4-methyl-6-phenylpyrimidines.
Keywords:4-methyl-6-phenyl-1  4-dihydropyrimidines  4-methyl-6-phenylpyrimidines  mesityl oxide  4  6  6-trimethyl-1  4-dihydropyrimidines  2-quinazolylguanidines  condensation  oxidation
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