Sesquiterpenes from the marine algicolous fungus Drechslera sp. |
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| Authors: | Ahmed Abdel-Lateff Tatsufumi Okino Walied M. Alarif Sultan S. Al-Lihaibi |
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| Affiliation: | 1. Deptartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, P.O. Box 80260, Jeddah 21589, Saudi Arabia;2. Faculty of Environmental Earth science, Hokkaido University, Sapporo 060-0810, Japan;3. Marine Chemistry Department, Faculty of Marine Sciences, King AbdulAziz University, P.O. Box 80207, Jeddah 21589, Saudi Arabia |
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| Abstract: | A marine fungal isolate, identified as Drechslera sp., was mass cultivated and found to produce a new naturally occurring seco-sativene type sesquiterpene helminthosporic acid (1) and three known sesquiterpenes, helminthosporol (2), drechslerine A (3) and (+) secolongifolene-diol (4). The structures of all compounds were determined by interpretation of their spectroscopic data 1D (1H and 13C), 2D (COSY, DQF, NOE, HSQC and HMBC) NMR, MS, UV and IR analyses. All compounds have been tested toward antioxidants, antimicrobial and antifouling effects. |
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| Keywords: | Marine microorganism Fungi Sesquiterpenes |
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