Ruthenium-catalyzed oxidative synthesis of 2-pyridones through C-H/N-H bond functionalizations |
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| Authors: | Ackermann Lutz Lygin Alexander V Hofmann Nora |
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| Affiliation: | Institut fu?r Organische und Biomolekulare Chemie, Georg-August-Universita?t, Tammannstrasse 2, 37077 Go?ttingen, Germany. Lutz.Ackermann@chemie.uni-goettingen.de |
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| Abstract: | ![]()
An inexpensive ruthenium catalyst enabled oxidative annulations of alkynes by acrylamides with ample scope, which allowed for the preparation of 2-pyridones employing various electron-rich and electron-deficient acrylamides as well as (di)aryl- and (di)alkyl-substituted alkynes. |
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