Synthesis,Crystal Structure and DNA Binding Property of Diaquadi(4-methylbenzoyloxy)bis[2-(4-pyridyl)-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide]cobalt(II)

Abstract  

A novel cobalt(II) complex of Co(4-MePhCOO)₂(NITpPy)₂(H₂O)₂] (1), where NITpPy is short for 2-(4-pyridyl)-4,4,5,5-tetramethylimidazoline-1-oxy 3-oxide(C₁₂H₁₆N₃O₂), was synthesized and structurally characterized by X-ray diffraction analysis. The X-ray diffraction analysis reveals that 1 crystallizes in the triclinic space group P-1 with a = 6.7910(10) ?, b = 12.4421(15) ?, c = 12.9169(16) ?, α = 89.8470(10)°, β = 89.8480(10)°, γ = 76.991(2)°, and Z = 1. The Co atom in the complex is located on the center of inversion and lies in a distorted octahedral geometry defined by an N₂O₄ donor set. The interaction of 1 with calf thymus DNA (CT-DNA) was investigated by UV–vis absorption and emission spectroscopy, which indicating that 1 could bind to DNA through electrostatic interaction.