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One-pot methodology for conversion of o-halogen nitrobenzenes to benzofuroxans |
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| Authors: | Elisa Leyva Socorro Leyva-Ramos Rogelio Jiménez-Cataño Telma A. de Luna-Méndez Agobardo Cárdenas-Chaparro |
| Affiliation: | 1. Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, San Luis Potosí, Méxicoelisa@uaslp.mx;3. Facultad de Ciencias Químicas, Universidad Autónoma de San Luis Potosí, San Luis Potosí, México |
| Abstract: | Reaction of o-halonitrobenzenes with sodium azide under reflux of DMF/H2O gives benzofuroxans in one step in moderate to good yields. This is a faster methodology compared to the conventional procedure involving the preparation and subsequent pyrolysis of o-nitrophenyl azides. For comparison, the reaction was also performed under phase-transfer catalysis. |
| Keywords: | Benzofuroxan heterocycle o-nitrophenyl azide SNAr |