Salicylaldehyde and dihydroisobenzofuran derivatives from the marine fungus Zopfiella marina |
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Authors: | Supichar Chokpaiboon Panida Unagul Sutichai Nithithanasilp Somjit Komwijit Wiwat Somyong Thanawut Ratiarpakul |
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Institution: | National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, Thailand |
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Abstract: | Two salicylaldehyde derivatives (1 and 2), a hydroxymethylphenol (3), five dihydroisobenzofuran (4–8) derivatives, and a 5-chloro-3-deoxyisoochracinic acid (9), together with a known 3-deoxyisoochracinic acid (10) were isolated from the marine fungus Zopfiella marina BCC 18240 (or NBRC 30420). The structures of these compounds were elucidated by extensive spectroscopic analysis. Compound 1 showed weak antituberculous activity against Mycobacterium tuberculosis H37Ra, and antibacterial activity against Bacillus cereus with MIC values of 25 and 12.5 μg/mL, respectively. |
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Keywords: | Salicylaldehyde derivative dihydroisobenzofuran obligate marine fungi Zopfiella marina |
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