Chemical constituents from the fruiting bodies of Phellinus igniarius |
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Authors: | Nguyen Tan Thanh Nguyen Ngoc Tuan Ping-Chung Kuo Doan Manh Dung Doan Lan Phuong Dinh Thi Truong Giang |
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Affiliation: | 1. School of Chemistry, Biology and Environment, Vinh University, Vinh City, Vietnam;2. Institute of Biotechnology and Food Technology, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Vietnam;3. School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan;4. Hue University of Science – Hue University, Hue City, Vietnam;5. Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, Cau Giay, Viet Nam;6. School of Natural Sciences Education, Vinh University, Vinh City, Vietnam |
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Abstract: | A new tirucallane-type triterpenoid igniarine (1), and four known compounds meshimakobnol A (2), meshimakobnol B (3), ergosterol (4) and ergosterol peroxide (5), were purified from the methanol extracts of the fruiting bodies of Phellinus igniarius (DC. ex Fr.) Quél. The structure of 1 was elucidated using a combination of 1D and 2D NMR techniques and HR-ESI-MS analyses. In addition, the isolated compounds were examined for their cytotoxicity against several tumour cell lines and part of the tested compounds demonstrated weak cytotoxicity. |
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Keywords: | Phellinus igniarius igniarine Hymenochaetaceae cytotoxicity |
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