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Chemical constituents from the fruiting bodies of Phellinus igniarius
Authors:Nguyen Tan Thanh  Nguyen Ngoc Tuan  Ping-Chung Kuo  Doan Manh Dung  Doan Lan Phuong  Dinh Thi Truong Giang
Affiliation:1. School of Chemistry, Biology and Environment, Vinh University, Vinh City, Vietnam;2. Institute of Biotechnology and Food Technology, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Vietnam;3. School of Pharmacy, College of Medicine, National Cheng Kung University, Tainan, Taiwan;4. Hue University of Science – Hue University, Hue City, Vietnam;5. Institute of Natural Products Chemistry, Vietnam Academy of Science and Technology, Cau Giay, Viet Nam;6. School of Natural Sciences Education, Vinh University, Vinh City, Vietnam
Abstract:
A new tirucallane-type triterpenoid igniarine (1), and four known compounds meshimakobnol A (2), meshimakobnol B (3), ergosterol (4) and ergosterol peroxide (5), were purified from the methanol extracts of the fruiting bodies of Phellinus igniarius (DC. ex Fr.) Quél. The structure of 1 was elucidated using a combination of 1D and 2D NMR techniques and HR-ESI-MS analyses. In addition, the isolated compounds were examined for their cytotoxicity against several tumour cell lines and part of the tested compounds demonstrated weak cytotoxicity.
Keywords:Phellinus igniarius  igniarine  Hymenochaetaceae  cytotoxicity
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