Four new anthraquinones from a soil actinomycete Streptomyces sp. WS-13394 and their bioactivities |
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Authors: | Zhaoyuan Wu Yani Zhang Wei Fang |
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Affiliation: | Hubei Biopesticide Engineering Research Centre, Hubei Academy of Agricultural Sciences, Wuhan, P. R. China |
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Abstract: | Further chemical study of secondary metabolites from the soil actinomycete Streptomyces sp. WS-13394 resulted in the isolation of four new alkylated anthraquinone analogues (5–8). Their structures were elucidated on the basis of extensive spectroscopic analysis, including HR-ESI-MS, 1D and 2D NMR. The new compounds, together with analogues obtained before (1–4), were tested for their in vitro cytotoxicity against Huh-7 and SGC-7901. |
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Keywords: | Alkylated anthraquinone Streptomyces sp. WS-13394 actinomycete cytotoxic |
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