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Vibrational spectroscopic study of human pigment gallstones and their insoluble materials |
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| Authors: | Gang Liu Da Xing Haimin Wang Jie Wu |
| Institution: | a Center of Analysis and Testing, Yunnan Normal University, Kunming 650092 Yunnan, People's Republic of China b Institute of Laser Life Science, South China Normal University, Guangzhou 510631 Guangdong, People's Republic of China c Department of Basic Medicine Science, Kunming Medical College, Kunming 650031 Yunnan, People's Republic of China |
| Abstract: | Proteins may play an important role in the formation of gallstones, but their secondary structure remains unclear in gallstones. In this paper, the insoluble materials of human pigment gallstones dissolved with chloroform, ethanol, ether and hydrochloric acid were studied by Fourier transform infrared spectroscopy. The results show that the insoluble materials of gallstones are mainly composed of bilirubinate salts and proteins. The secondary structure of proteins in pigment gallstones may contain more  -helix. |
| Keywords: | Gallstone Insoluble materials Protein Fourier transform infrared spectroscopy |
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