Improved microwave-assisted catalyst-free synthesis of 9-aryl-5,9-dihydropyrimido[4,5-d][1,2,4]triazolo[1,5-a]pyrimidine-6,8(4H,7H)-dione derivatives |
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Authors: | Mahnaz Farahi Bahador Karami Zohreh Banaki |
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Institution: | Department of Chemistry, Yasouj University, Yasouj 75918-74831, Iran |
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Abstract: | A green regioselective synthesis of some new and known 9-aryl-5,9-dihydropyrimido4,5-d]1,2,4]triazolo1,5-a]pyrimidine-6,8(4H,7H)-diones has been described via the microwave-assisted one-pot reaction of 3-amino-1H-1,2,4-triazoles, aromatic aldehydes and barbituric acids under solvent- and catalyst-free conditions. This operationally simple procedure is less laborious and provides a better scope than previously reported procedures. |
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Keywords: | 9-Aryl-5 9-dihydropyrimido[4 5-d]-[1 2 4]triazolo[1 5-a]pyrimidine-6 8(4H 7H)-diones Barbituric acids 3-Amino-1H-1 2 4-triazoles Aryl aldehydes Microwave-assisted synthesis |
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