Polymeric Nitrofuran Derivatives. II. Chemical Modification of Functionalized Resins with Nitrofuran Derivatives |
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| Authors: | N. Moszner M. Hartmann H. Bergmann H. Schütz E. Schütz G. Schwachula |
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| Affiliation: | 1. Department of Chemistry Technical , University Merseburg , 0-4200, Merseburg, Federal Republic of Germany;2. Institute of Organic and Macromolecular Chemistry Friedrich-Schiller-University , 0-6900, Jena, Federal Republic of Germany;3. Institute of Communal Hygiene Friedrich-Schiller-University , 0-6900, Jena, Federal Republic of Germany;4. Chemie AG Bitterfeld-Wolfen , 0-4400, Bitterfeld, Federal Republic of Germany |
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| Abstract: | Polymeric nitrofuran derivatives have been synthesized by chemical modification of macroporous styrene-divinylbenzene copolymers with low molecular weight nitrofurans. The 5-nitrofuryl groups are covalently attached to the polymeric carrier by azomethine, ester, N-alkyl, and sulfamide links, respectively. Comparative hydrolysis studies and biological tests of the modified resins suggested that the polymeric carrier-bound nitrofurans are antimicrobially active. The polymeric nitrofurans have been characterized by IR and “C-solid-NMR spectroscopy”. |
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| Keywords: | Chitosan Polyacrylamide Blend films Hydrogen bonds Miscibility |
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