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Highly regio- and stereoselective synthesis of tricyclic frameworks using Baylis-Hillman derivatives
Authors:Manickam Bakthadoss  Nagappan Sivakumar  Govindan Sivakumar  Gandhi Murugan
Affiliation:Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai 600 025, Tamil Nadu, India
Abstract:A simple and convenient synthetic route for the synthesis of tricyclic chromeno[4,3-b]pyrrolidine frameworks using Baylis-Hillman bromides involving in situ formation of an imine, decarboxylation and a [3+2] cycloaddition sequence is described.
Keywords:Baylis-Hillman reaction   Intramolecular [3+2]cycloaddition   Azomethine ylides   1,3-Dipolar cycloaddition   Tricyclic compounds
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