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Synthesis of substituted benzimidazoles via tosylation of N-aryl amidoxime |
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| Authors: | Yuhei Yamamoto Takayuki Tsuritani Toshiaki Mase |
| Institution: | Process Research Preclinical Development, Banyu Pharmaceutical Co., Ltd, 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan |
| Abstract: | Tosylation of N-aryl amidoxime in the presence of TEA produces the corresponding benzimidazoles in high yields. |
| Keywords: | Benzimidazoles N-Aryl amidoximes Imidoyl chlorides Nitrile oxides |
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