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One-pot synthesis of pyrimidines under solvent-free conditions
Affiliation:1. Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, 65174 Hamedan, Iran;2. School of Chemistry, University College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran;3. Department of Chemistry, Urmia University, 57154 Urmia, Iran
Abstract:N,N,N’,N’-Tetrabromobenzene-1,3-disulfonamide was used as an efficient catalyst for the one-pot synthesis of pyrimidine derivatives in excellent yields from triethoxymethane, ammonium acetate, and various ketone derivatives at 100–110 °C under solvent-free conditions.
Keywords:Pyrimidine  Multicomponent reaction  Triethoxymethane  Ammonium acetate  Solvent-free  TBBDA
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