One-pot synthesis of pyrimidines under solvent-free conditions |
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Affiliation: | 1. Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, 65174 Hamedan, Iran;2. School of Chemistry, University College of Science, University of Tehran, PO Box 14155-6455, Tehran, Iran;3. Department of Chemistry, Urmia University, 57154 Urmia, Iran |
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Abstract: | N,N,N’,N’-Tetrabromobenzene-1,3-disulfonamide was used as an efficient catalyst for the one-pot synthesis of pyrimidine derivatives in excellent yields from triethoxymethane, ammonium acetate, and various ketone derivatives at 100–110 °C under solvent-free conditions. |
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Keywords: | Pyrimidine Multicomponent reaction Triethoxymethane Ammonium acetate Solvent-free TBBDA |
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