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Isolation and Structure Elucidation of Nortriterpenoids from Schisandra rubriflora
Authors:Wei‐Lie Xiao  Jian‐Xin Pu  Rui‐Rui Wang  Liu‐Meng Yang  Xiao‐Li Li  Sheng‐Hong Li  Rong‐Tao Li  Sheng‐Xiong Huang  Yong‐Tang Zheng  Han‐Dong Sun
Institution:1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, P.?R. China, (phone: +86‐871‐5223251;2. fax: +86‐871‐5216343);3. Key Laboratory of Animal Models and Human Disease Mechanisms and Laboratory of Molecular Immunopharmacology, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, P.?R. China
Abstract:Seven new highly oxygenated nortriterpenoids, rubriflorins D–J ( 1 – 7 ), were isolated from the leaves and stems of Schisandra rubriflora, and their structures were elucidated on the basis of extensive analysis of spectroscopic data. These new compounds feature the opening of ring A compared with related known nortriterpenoids isolated from the genus Schisandra and showed weak activity against HIV‐1.
Keywords:Nortriterpenoids  Schisandra rubriflora  Rubriflorins D       J  HIV  Anti‐HIV‐1 activity
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