New Nitrogenous Bisabolene‐Type Sesquiterpenes from a Hainan Sponge Axinyssa aff. variabilis |
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| Authors: | Shui‐Chun Mao Yue‐Wei Guo Rob van Soest Guido Cimino |
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| Affiliation: | 1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zu Chong Zi Rd. 555, Zhangjiang Hi‐Tech Park, Shanghai 201203, P.?R. China, (phone: 86‐21‐50805813);2. Zoological Museum, University of Amsterdam, Amsterdam, The Nederlands;3. Istituto di Chimica Biomolecolare‐CNR, I‐80078 Napoli, Italy |
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| Abstract: | Two new uncommon nitrogenous sesquiterpenes, 11‐ethoxy‐3‐formamidotheonellin ( 1 ) and 7‐ethoxy‐3‐formamidobisabolane‐8,10‐diene ( 2 ), together with two known related sesquiterpenes, 3‐formamidotheonellin (=theonellin formamide; 3 ) and theonellin isothiocyanate ( 4 ), were isolated from the Hainan sponge Axinyssa aff. variabilis. Their structures were determined on the basis of extensive spectroscopic analysis and by comparison of their NMR data with those of known compounds. |
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| Keywords: | Sponges Axinyssa aff. variabilis Sesquiterpenes Bisabolene |
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