Structure‐Based Macrocyclization Yields Hepatitis C Virus NS5B Inhibitors with Improved Binding Affinities and Pharmacokinetic Properties |
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Authors: | Maxwell D. Cummings,Tse‐I Lin,Lili Hu,Abdellah Tahri,David McGowan,Katie Amssoms,Stefaan Last,Benoit Devogelaere,Marie‐Claude Rouan,Leen Vijgen,Jan Martin Berke,Pascale Dehertogh,Els Fransen,Erna Cleiren,Liesbet van der Helm,Gregory Fanning,Kristof Van Emelen,Origè ne Nyanguile,Kenny Simmen,Pierre Raboisson,Sandrine Vendeville |
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Abstract: | |
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Keywords: | Hepatitis‐C‐Virus Inhibitoren Makrocyclen Pharmakokinetik Polymerasen |
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