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Selective synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles in water at ambient temperature |
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| Authors: | Peyman Salehi Minoo Dabiri Somayeh Otokesh |
| Affiliation: | a Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, PO Box 19835-389, Evin, Tehran, Iran b Department of Chemistry, Faculty of Sciences, Shahid Beheshti University, Evin, Tehran, Iran c Department of Chemistry, Faculty of Sciences, Bu-Ali Sina University, Hamadan, Iran |
| Abstract: | A highly selective synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzimidazoles from the reaction of o-phenylenediamines and aromatic aldehydes in the presence of silica sulfuric acid is reported. The reactions were performed in ethanol or water and the catalyst could be reused for several runs. |
| Keywords: | Heterocycles Benzimidazole Heterogenous catalysis Water Silica sulfuric acid |
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