Straightforward synthesis of 1,6-dioxaspiro[4.4]nonanes |
| |
| Authors: | Jaisiel Melé ndez |
| |
| Affiliation: | Departamento de Química Orgánica, Facultad de Ciencias, Instituto de Síntesis Orgánica (ISO), Universidad de Alicante, Apdo. 99, 03080 Alicante, Spain |
| |
| Abstract: | Diols 2, easily prepared by a DTBB-catalysed lithiation of the dithioether 1 in the presence of different carbonyl compounds, react with ozone in dichloromethane at −78 °C leading, after treatment with thiourea at 20 °C, to the corresponding substituted 1,6-dioxaspiro[4.4]nonanes 3. |
| |
| Keywords: | Unsaturated 1,7-diols 1,6-Dioxaspiro[4.4]nonanes Spiroketals Ozonolysis Cyclization |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
