|
|||||
|
|
Exiguolide, a new macrolide from the marine sponge Geodia exigua |
|
| Authors: | Shinji Ohta Mylene M Uy Mihoko Yanai Toshifumi Hirata |
| Institution: | a Nagahama Institute of Bio-Science and Technology, 1266 Tamura-cho, Nagahama, Shiga 526-0829, Japan b Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan c Natural Science Center for Basic Research and Development, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan |
| Abstract: | A new 20-membered macrolide designated exiguolide has been isolated from the marine sponge Geodia exigua, and its structure determined by interpretation of spectroscopic data. Exiguolide specifically inhibited fertilization of sea urchin (Hemicentrotus pulcherrimus) gametes but not embryogenesis of the fertilized egg. |
| Keywords: | Marine sponge Geodia exigua Macrolide |
| 本文献已被 ScienceDirect 等数据库收录！ | |