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An efficient palladium-catalyzed Heck coupling of aryl chlorides with alkenes
Authors:Chenyi Yi
Affiliation:Department of Chemistry, Tsinghua University, Innovative Catalysis Program, Key Laboratory of Organic Optoelectronics and Molecular Engineering of Ministry of Education, Beijing 100084, China
Abstract:
Catalyst system PdCl2(PCy3)2/Cs2CO3 in dioxane was found to be the efficient catalyst system for Heck cross-coupling reactions of deactivated, neutral, and activated aryl chlorides with a variety of alkenes under mild conditions to afford selectively E-arylated alkenes in good to excellent yields.
Keywords:Alkene   Aryl chloride   Catalysis   Heck coupling   Palladium
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