Solid phase synthesis of praziquantel |
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Authors: | Shaimaa El-Fayyoumy Wafaa Mansour |
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Institution: | a School of Chemistry, University of Sydney, NSW 2006, Australia b Department of Biological and Chemical Sciences, Queen Mary, University of London, Mile End Road, London E1 4NS, UK |
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Abstract: | The first solid phase synthesis of the important anthelmintic praziquantel is described. The synthesis is rapid and efficient. The method may be extended to the synthesis of libraries of urgently needed replacements for this drug. |
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