A non-catalytic regioselective approach to the synthesis of (E)-stilbenes from suitably functionalized 2H-pyran-2-ones |
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| Authors: | Ramendra Pratap PR Maulik |
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| Institution: | a Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow 226001, India
b Molecular and Structural Biology Division, Central Drug Research Institute, Lucknow 226001, India |
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| Abstract: | Highly functionalized (E)-stilbenes 3a-m and 4-aryl-6-styryl-pyran-2-ylidineacetonitriles 4a-b have been prepared and delineated through the ring transformation of 6-aryl-3,4-disubstituted-2H-pyran-2-ones 1 with commercially available (E/Z)-4-phenyl-3-buten-2-one 2 without the use of any catalyst. |
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| Keywords: | Stilbene Ring transformation 2H-Pyran-2-ones |
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