A new one-pot three-component synthesis of 2,4-diamino-5<Emphasis Type="Italic">H</Emphasis>-chromeno[2,3-<Emphasis Type="Italic">b</Emphasis>]pyridine-3-carbonitrile derivatives |
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| Authors: | Ahmad Shaabani Fatemeh Hajishaabanha Hamid Mofakham and Ali Maleki |
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| Institution: | (1) Molecular and Structural Biology Division, Central Drug Research Institute, P.O. Box 173, Lucknow, 226001, India;(2) Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, 226001, India; |
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| Abstract: | In this study, a three-component one-pot synthesis of new 2,4-diamino-5H-chromeno2,3-b]pyridine-3-carbonitriles derived from 2-amino-1,1,3-tricyanopropene, salicylic aldehydes and secondary cyclic amines is reported.
The reaction is conducted in ethanol at ambient temperature in good-to-excellent yields. |
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