Solvent selectivity in the resolution of some regioisomeric and diastereomeric prostaglandin intermediates on silica |
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| Authors: | M L?hmus I Kirjanen M Lopp U Lille |
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| Institution: | Estonian Academy of Sciences, Tallinn, U.S.S.R. |
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| Abstract: | The possibilities of predicting the selectivity in the resolution of regioisomeric and diastereomeric prostaglandin intermediates on silica gel was investigated. A satisfactory correlation between log alpha and the solvent localization parameters m and m0 was obtained, confirming the importance of solvent-solute localization in determining alpha values. The results will be useful in developing further the theory of the selectivity of resolution. |
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