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Asymmetric synthesis of aldehydes via alkylation of lithiated chiral α-phenethylimines |
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| Authors: | Robert R Fraser Fuminori Akiyama Jacques Banville |
| Institution: | Department of Chemistry, University of Ottawa, Ottawa, K1N 9B4, Canada |
| Abstract: | The lithiation and alkylation of three aldehydes in the form of their α-phenethylimines has been shown to yield chiral α-alkylaldehydes of 67–70% optical purity. |
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