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Chemistry of ketene acetals II. A simple route to 2,2-dialkoxytetrahydrofurans, γ-butyrolactones, 2-(5H)-furanones and 2-alkoxy-4,5-dihydrofurans
Authors:JW Scheeren  FJM Dahmen  CG Bakker
Institution:Department of Organic Chemistry, Catholic University, Toernooiveld, 6525 ED Nijmegen, The Netherlands
Abstract:2,2-Dialkoxytetrahydrofurans 3 (a,b) have been synthesized from epoxides 1 and ketene acetals 2 using ZnCl2 as a catalyst. By simple reactions compounds 3 were converted into γ-butyrolactones 5, 2-(5H)-furanones 7 and 2-alkoxy-4,5-dihydrofurans 8.
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