Preparation of cross-linked poly[(epsilon-caprolactone)-co-lactide] and biocompatibility studies for tissue engineering materials |
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Authors: | Miyasako Hiroshi Yamamoto Kazuya Nakao Aiko Aoyagi Takao |
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Affiliation: | Department of Nanostructure and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University, 1-21-40 Korimoto, Kagoshima 890-0065, Japan. |
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Abstract: | In this study, cross-linked materials were prepared using the branched macromonomer with different CL/LA molar ratios, and feasibility studies for tissue engineering were carried out. The thermal and mechanical properties of these materials depended on the CL/LA compositions; however, there was no change in the wettability of each material. The HeLa cells adhesion and growth on the CL-LA7030c were equal to that on the commercially available polystyrene dish. The protein absorption experiment using the FBS proteins revealed that the materials with well-grown cells showed better adhesion of the proteins. [photo: see text] |
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Keywords: | chain poly(ε‐caprolactone) poly(lactide) protein protein adsorption scaffold tissue engineering |
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